Too much taurine side effects9/3/2023 ![]() Although taurine possesses many functions in mammals, its cytoprotective actions have attracted the most attention, as they dramatically alter the health and nutritional status of various species. Taurine is a β-amino acid found in very high concentration in most cells, with levels particularly high in excitable tissues. The review also addresses the functions of taurine (regulation of antioxidation, energy metabolism, gene expression, ER stress, neuromodulation, quality control and calcium homeostasis) underlying these therapeutic actions. In addition, taurine is extremely effective in the treatment of the mitochondrial disease, mitochondrial encephalopathy, lactic acidosis, and stroke-like episodes (MELAS), and offers a new approach for the treatment of metabolic diseases, such as diabetes, and inflammatory diseases, such as arthritis. The present review summarizes studies supporting a role of taurine in the treatment of diseases of muscle, the central nervous system, and the cardiovascular system. Today, taurine has been approved for the treatment of congestive heart failure in Japan and shows promise in the treatment of several other diseases. The discovery that taurine is an effective therapy against congestive heart failure led to the study of taurine as a therapeutic agent against other disease conditions. These findings have spurred interest in the potential use of taurine as a therapeutic agent. In some species, taurine is an essential nutrient but in man it is considered a semi-essential nutrient, although cells lacking taurine show major pathology. Double-blind crossover study with levorotatory form of hydroxytryptophan in patients with degenerative cerebellar diseases.Taurine is an abundant, β-amino acid with diverse cytoprotective activity. Double-blind study of 5-hydroxytryptophan versus placebo in the treatment of primary fibromyalgia syndrome. 5-hydroxytryptophan: A clinically effective serotonin precursor. ![]() 5-hydroxy-L-tryptophan suppresses food intake in food-deprived and stressed rats. You can learn more about how we ensure our content is accurate and current by reading our editorial policy. Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. Last medically reviewed on August 20, 2019
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